Sika’s near and long-term emissions reduction targets, aiming for net-zero emissions by 2050, have been validated by the Science Based Targets initiative (SBTi)1. This important achievement underscores Sika’s commitment to sustainability and its proactive role in decarbonizing the construction and automotive industries.   By 2032, Sika is committed to reducing its greenhouse gas (GHG) emissions by 50.4% compared to the 2022 baseline, for scope 1 and scope 2 emissions, whilst advancing its growth strategy. These include direct emissions from owned or controlled...

Read more

Key insights • Trends indicate a robust economy supported by strong consumer spending and transformative wealth transfers. CLA is predicting the rest of 2024 is characterized by a sense of resilience and optimism. • Market sentiment is leaning toward a growth mindset, with the economy showing strength and businesses focusing on expanding and managing costs effectively. • Within investing, a diversified portfolio is strategically designed to mitigate market volatility. It serves to both preserve and augment capital. Curious about the many benefits of...

Read more

On February 23, the Food and Drug Administration (FDA) withdrew approval of Pepaxto (melphalan flufenamide), a drug that it had previously granted accelerated approval for treatment of multiple myeloma. The decision came after a post-marketing, confirmatory study of Pepaxto failed to confirm the drug’s clinical benefit, and FDA determined that available evidence demonstrated that Pepaxto was not shown to be safe or effective under its conditions of use. Although accelerated approval remains an important pathway for sponsors to make...

Read more

Unpacking the EU leadership debate 2024 With less than two weeks until the first Europeans head to the poll, on Tuesday (21 May), Brussels think tank Bruegel and the Financial Times hosted the ‘Economic choices for Europe: EU leadership debate 2024’ to debate the economic policy positions of the main EU parties and their lead candidates. Those in attendance were as follows: Sandro Gozi (lead candidate for the centrist Renew Europe), Ursula von der Leyen (President of the European Commission and lead candidate for...

Read more

Article by Marie-Pierre Pasdelou, Lise Byelyayeva, Susanna Malmström, Sylvie Pucheu, Marie Peytavy, Hugo Laullier, Donald B. Hodges, Abraham R. Tzafriri, Gaëlle Naert | Hearing loss constitutes a major global health concern impacting approximately 1.5 billion people worldwide. Its incidence is undergoing a substantial surge with some projecting that by 2050, a quarter of the global population will experience varying degrees of hearing deficiency. Environmental factors such as aging, exposure to loud noise, and the intake of ototoxic medications are implicated...

Read more

Overview:  The dollar was aided yesterday by the hawkish FOMC minutes and the backing up of US rates. The greenback has stabilized today and is softer against all the G10 currencies. The stronger eurozone PMI masks divergence between Germany and France but keeps the recovery narrative intact. The dollar's broad gains pressured the yuan, and the PBOC's dollar reference rate was set at its highest since January. Favorable guidance by Nvidia is helping lift US index futures today, especially the NASDAQ....

Read more

Due to increased travel to France for the eightieth anniversary of D-Day and the 2024 Summer Olympic Games, the U.S. Department of State expects significant delays in visa processing in France in 2024. Individuals seeking to obtain a U.S. visa in Europe this year may want to begin the visa application process as soon as possible. Quick Hits • With the upcoming Summer Olympics and D-Day celebrations, individuals planning to obtain a visa in Paris should anticipate scheduling delays and plan...

Read more

On May 21, 2024, the Council of the European Union (the Council) formally signed off on the latest draft of the European Union’s (EU) Artificial Intelligence Act (AI Act) (see the press release here). This marks the final seal of approval from the EU legislators. The text will officially become law once it is signed by Presidents of the European Parliament and of the Council and published in the Official Journal of the EU. This could take place within the...

Read more

The OECD’s Pillar Two is here - many jurisdictions have locally enacted legislation that became effective on January 1, 2024. Pillar Two generally applies to multinational companies (MNCs) with revenue of at least EUR €750M, and while the global legislative process and further OECD guidance will continue to evolve, it requires MNCs to evaluate their potential global minimum tax expense under Pillar Two through a data intensive calculation process. This presents a significant operational challenge that may result in...

Read more